Interventional Radiology Applications

ABLATING TISSUE WITHOUT BURNING

PERCRYO® ABLATION VERSUS
RADIOFREQUENCY ABLATION

HIGHLY VISIBLE UNDER IMAGE GUIDANCE
  • CT imaging produces a 40 Hounsfield unit drop in attenuation.1
  • Iceball visualization allows for monitoring of adjacent structures.2
LESS PAIN DURING & POST-PROCEDURE
  • Ice formation produces a natural pain anesthetic.3
  • Reduced narcotics use during and post procedures shown in renal study.3
DOES NOT DESTROY COLLAGEN
  • Ice allows the natural tissue architecture to remain intact.4
  • Treatments are possible near and around critical vessels and structures.4
MULTIPLE CRYOPROBES MAY BE USED SIMULTANEOUSLY
  • Multiple cryoprobes used simultaneously can create a large ablation zone.5
  • Multiple cryoprobes allow treatment of multiple tumors concurrently.6
ICE PROPAGATION IS PREDICTABLE & REPRODUCIBLE6

Demarcations between necrotic zone and normal hepatic tissue for PerCryo® Ablation and Radiofrequency Ablation.

(asterisk) : complete necrosis
(arrow) : partial necrosis

PerCryo® Ablation

Radiofrequency Ablation

PERCRYO® ABLATION
APPLICATIONS

RENAL TUMORS
  • Data suggest significantly lower rates of local tumor progression versus Radiofrequency Ablation.8
  • Freezing does not injure the collecting system.9
  • Appropriate for exophytic and central lesions.10
  • Provides nephron-sparing treatment option.11
PULMONARY & THORACIC TUMORS
  • Ability to ablate tissue immediately adjacent to central bronchi.4
  • Offers an alternative for poor surgical candidates.4
  • Provides palliative treatment for thoracic tumors.13
LIVER METASTASES
  • Highly visible ice increases the ability to protect adjacent structures.9
  • Can be performed on an outpatient basis with concious sedation.5
  • Treatment alternative for patients with tumors near peripheral sites (diaphragm/chest wall) with use of intraperitoneal 5% dextrose in water.5
FREEZING OF NERVE TISSUE IN PAIN MANAGEMENT/CRYOANALGESIA14
  • Significant reduction in pain scores for post thoracotomy pain.15
  • Performed with local anethesia and sedation.15
  • Effect lasts from weeks to months.15

CRYOCARE CS® BASIC SYSTEM

The CRYOCARE CS Basic System is a streamlined cryoablation system, designed specifically for the percutaneous ablation market.

CRYOCARE CS® BASIC SPECIFICATIONS

System Size (L x W x H) Approximately 30” x 24” x 40”
Weight <300lbs
Electrical 120/230 VAC 50/60 Hz 4 Amps RMS
Fuse T6 3A 250V


1 Sandison GA, et al: X-ray CT Monitoring of Iceball Growth and Thermal Distribution During Cryosurgery. Phys Med Biol 43: 3309-3324, 1998.
2 Atwell T, et al: Percutaneous Renal Cryoablation: Experience Treating 115 Tumors. J Urol; 179:2136-2141, 2008.
3 Allaf ME, et al: Pain Control Requirements for Percutaneous Ablation of Renal Tumors: Cryoablation versus Radiofrequency Ablation–Initial Observations. Radiology 237: 366-370, 2005.
4 Wang H, et al: Thoracic Masses Treated with Percutaneous Cryotherapy: Initial Experience With More Than 200 Procedures. Radiology 235: 289-298, 2005.
5 Hinshaw JL and Lee FT Jr: Cryoablation for Liver Cancer. Tech Vasc Interventional Rad 10:47-57, 2007.
6 Data on file.
7 Shock SA, et al: Hepatic Hemorrhage Caused by Percutaneous Tumor Ablation: Radiofrequency Ablation versus Cryoablation in a Porcine Model. Radiology 236: 125-131, 2005
8 Kunkle DA and Uzzo RG: Cryoablation or Radiofrequency Ablation of the Small Renal Mass: A Meta-analysis. Cancer 113: 2671-2680, 2008.
9 Rosenberg MD, et al: Percutaneous Cryoablation of Renal Lesions With Radiographic Ice Ball Involvement of the Renal Sinus: Analysis of Hemorrhagic and Collecting System
Complications. AJR; 196:935-939, 2011.
10 Atwell T, et al: Percutaneous Renal Cryoablation: Experience Treating 115 Tumors. J Urol 179:2136-2141, 2008.
11 Desai MM, et al: Current Status of Cryoablation and Radiofrequency Ablation in the Management of Renal Tumors. Curr Opin Urol 12: 387-393, 2002.
13 Aoun H, et al: Percutaneous Cryotherapy of Lung Tumors: CT Fluoroscopic Guidance. 2006 RSNA Abstract.
14 Cryocare CS TM System Operator’s Manual.
15 Moore M, et al: CT Guided Percutaneous Cryoneurolysis for Post Thoracotomy Pain Syndrome. Acad Radiol 17:603-606, 2010.